P510Obtention and characterization of acellular myocardial scaffold for cardiac tissue engineering
نویسندگان
چکیده
منابع مشابه
Fabrication and characterization of nanofibrous tricuspid valve scaffold based on polyurethane for heart valve tissue engineering
Objective(s): Tissue engineering represents a new approach to solve the current complications of the heart valve replacements by offering viable valve prosthesis with growth and remodeling capability. In this project, electrospinning and dip coating techniques were used to fabricate heart valve constructs from medical grade polyurethane (PU). Methods: Fir...
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. در رســاله ی حاضر، ابتدا داربست نانوالیاف سه بعدی متخلخل به روش الگوبرداری تصویری شبیه سازی شد. با استفاده از طراحی آزمایش به روش تاگوچی پس از ساخت داربست های پلی (3- هیدروکسی بوتیرات) (p3hb) شناسایی رفتار پارامترهای موادی مثل لزجت سیال پلیمر، فراریت و رسانایی الکتریکی محلول پلیمری و پارامترهای دستگاهی مثل دبی حجمی سیال، ولتاژ الکتریکی و فاصله نازل تا جمع کننده صورت گرفت. بعد از محاسبه ی خصوص...
fabrication and characterization of spongy denuded amniotic membrane based scaffold for tissue engineering
objective: as a biological tissue material, amniotic membrane (am) has low immunogenicity and to date has been widely adopted in clinical practice. however, some features such as low biomechanical consistency and rapid biodegradation is limited the application of am. therefore, in this study, we fabricated a novel three-dimensional (3d) spongy scaffold made of the extracellular matrix (ecm) of ...
متن کاملMyocardial scaffold-based cardiac tissue engineering: application of coordinated mechanical and electrical stimulations.
Recently, we developed an optimal decellularization protocol to generate 3D porcine myocardial scaffolds, which preserve the natural extracellular matrix structure, mechanical anisotropy, and vasculature templates and also show good cell recellularization and differentiation potential. In this study, a multistimulation bioreactor was built to provide coordinated mechanical and electrical stimul...
متن کاملRGD-modified acellular bovine pericardium as a bioprosthetic scaffold for tissue engineering.
Acellular biological tissues, including bovine pericardia (BP), have been proposed as natural biomaterials for tissue engineering. However, small pore size, low porosity and lack of extra cellular matrix (ECM) after native cell extraction directly restrict the seed cell adhesion, migration and proliferation and which is a vital problem for ABP's application in the tissue engineered heart valve ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2014
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvu091.182